What constitutes a "Designer" enhancement is a bit confusing, since I'm sure things that we might consider to be Designer issues are often ultimately native client issues. So what I'm giving is my top three things that affect design work for me, whereever they might occur...
1) Allow changing of *all* sizing controls to pixels via preferences, a la Photoshop.
2) View - Show - All Hotspot Borders, to make visible all Hotspots on the screen while in Designer.
3) This issue...
http://www-10.lotus.com/ldd/nfr6forum.nsf/55c38d716d632d9b8525689b005ba1c0/131cfd95c77d11ec85256c390071e9a9?OpenDocument
By the way Debbie, thanks for asking! :)